| Date | Day | Opponent | Site | Time/Result | Record |
| Sept. 2 | Mon. | The Citadel* | Charleston, SC | W 3-0 | 1-0, 1-0 |
| Sept. 6 | Fri. | Butler^ | Greenville, SC | W 4-0 | 2-0, 1-0 |
| Sept. 8 | Sun. | Creighton^ | Greenville, SC | W 4-2 |
3-0, 1-0 |
| Sept. 13 | Fri. | Bradley# | Notre Dame, Ind. | T 0-0 (2OT) |
3-0-1, 1-0 |
| Sept. 15 | Sun. | Notre Dame# | Notre Dame, Ind. | L 2-1 (2OT) | 3-1-1, 1-0 |
| Sept. 21 | Sat. | UNC Greensboro* | Greenville, SC | 4-1-1, 2-0 | |
| Sept. 24 | Tues. | Wofford* | Spartanburg, SC | W 3-0 | 5-1-1, 3-0 |
| Sept. 27 | Fri. | Faifield$ | Clemson, SC | W 4-3 | 6-1-1, 3-0 |
| Sept. 29 | Sun. | Gonzaga$ | Clemson, SC | W 2-0 | 7-1-1, 3-0 |
| Oct. 2 | Wed. | Appalachian State* | Greenville, SC | W 3-2 (2OT) | 8-1-1, 4-0 |
| Oct. 5 | Sat. | St. Louis | St. Louis, Mo. | L 2-0 | 8-2-1, 4-0 |
| Oct. 9 | Wed. | UNC Asheville | Greenville, SC | W 2-0 | 9-2-1, 4-0 |
| Oct. 16 | Wed. | Clemson | Clemson, SC |
Cancelled
|
|
| Oct. 19 | Sat. | College of Charleston* | Greenville, SC | W 1-0 | 10-2-1, 5-0 |
| Oct. 21 | Mon. | Lipsomb | Greenville, SC | W 3-0 | 11-2-1, 5-0 |
| Oct. 27 | Sun. | South Carolina | Columbia, SC | W 1-0 | 12-2-1, 5-0 |
| Oct. 30 | Wed. | Georgia Southern* | Statesboro, Ga. | W 1-0 | 13-2-1, 6-0 |
| Nov. 2 | Sat. | VMI* | Lexington, Va. | W 2-0 | 14-2-1, 7-0 |
| Nov. 10 | Sun. | Davidson* | Greenville, SC | W 3-0 | 15-2-1, 8-0 |
| Nov. 14 | Thurs. | Wofford** | Charleston, SC | W 3-0 | 16-2-1 |
| Nov. 16 | Sat. | UNCG | Charleston, SC | W 3-0 | 17-2-1 |
| Nov. 23 | Sat. | Loyola (Md.) | Greenville, SC | W 2-0 | 18-2-1 |
| Nov. 27 | Wed. | Virginia Commonwealth | Richmond, VA | W 0-0 (4-2) | 19-2-1 |
| Dec. 1 | Sun. | Stanford | Stanford, Calif. | L 2-1 (2OT) | |
| Dec. 8 | Sun. | NCAA Fourth Round | TBA | TBA | |
| Dec. 13 | Fri. | Men's College Cup | TBA | TBA | |
| Dec. 15 | Sun. | Men's College Cup | TBA | TBA |
* - SoCon Match
** - SoCon Tournament
^ - Spinx/LandRover Furman Invitational
# - Notre Dame Tournament
$ - Clemson/Nike Soccer Invitational