Study Questions - Other Deviations from HWE
Relevant Readings: chapter 6
What type of selection is this? How will delta-p change over the course of several generations? Why?
| p=0.3 q = 0.7 | AA | Aa | aa | |
| parental zygotes | 0.09 | 0.42 | 0.49 | = 1.00 |
| prob of survival | 0.6 | 0.8 | 0.4 | |
| rel. fitness | ||||
| genotypic frequencies in the reproductive adults | ||||
| gene frequencies in the gene pool | ||||
| Genotypic frequencies in the F1 |
4) Consider this population (yes, it's different):
| p=0.3 q = 0.7 | AA | Aa | aa | |
| parental zygotes | 0.09 | 0.42 | 0.49 | = 1.00 |
| prob of survival | 0.6 | 0.4 | 0.8 | |
| rel. fitness | ||||
| genotypic frequencies in the reproductive adults | ||||
| gene frequencies in the gene pool | ||||
| Genotypic frequencies in the F1 |
What will happen over time? Where will p equilibrate?
1) Consider a population with p = 0.8, q = 0.2, and a mutation rate of a-->A of 0.00003. What wil the new gene frequencies be after one generation of mutation?
2) Suppose there was also mutation of A--> a at a rate of 0.00004? What would delta-q be? At what frequency would q equilibrate? Prove this by plugging that gene frequency in and testing for delta-q... what do you get? Is that right?
3) Consider two populations. 1: p = 0.8, q= 0.2..... 2: p = 0.4, q = 0.6. Suppose migration occurs from 1 to 2, such that migrants represent 10% of the population... what will the new gene frequencies be in Pop 2?
What is the Genetic Distance between these populations?
4) Consider a population, p = q = 0.5, in HWE. Suppose there is exclusive positive assortative mating for this trait. How will the genotypic frequencies change over 2 generations?
5) How do the effects of positive assortative mating and inbreeding differ?
6) All homozygotes are NOT inbred. Explain the two ways that the 'A' alleles can relate to each other, and why this distinction is important.
7) List 4 effects that inbreeding has on a population.
8) Calculate F for the following population:
| p=0.3 q = 0.7 | AA | Aa | aa | |
| parental zygotes | 0.18 | 0.24 | 0.58 | = 1.00 |